Meridia works on the appetite control center of the brain by decreasing the amounts of several chemicals, called neurotransmitters. These chemicals carry messages, such as "I'm hungry," from the brain to the rest of the body. Meridia blocks these chemicals and their messages, so someone doesn't feel as hungry.

Before using this drug, tell your doctor your entire medical history, including: any allergies (especially drug allergies), liver or kidney disease, high blood pressure, heart disease, history of stroke or seizures, certain eating disorders (e.g., anorexia nervosa), glaucoma (narrow angle), history of gallstones.

Limit alcohol intake, as it may worsen certain side effects of Meridia.
Since this drug may cause dizziness or fatigue, use extreme caution if operating machinery or performing hazardous tasks (e.g., driving).

It is recommended that women of child-bearing age should use effective birth control while taking Meridia. This drug is not recommended for use during pregnancy. Consult your doctor before using this drug.

It is not known whether this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Elderly patients may be more sensitive to the effects of this drug. Use cautiously.